Comparison of the Inhibition of Monoamine Oxidase and Butyrylcholinesterase Activities by Infusions from Green Tea and Some Citrus Peels
Identifieur interne : 000B51 ( Main/Exploration ); précédent : 000B50; suivant : 000B52Comparison of the Inhibition of Monoamine Oxidase and Butyrylcholinesterase Activities by Infusions from Green Tea and Some Citrus Peels
Auteurs : Ayokunle O. Ademosun [Nigeria] ; Ganiyu Oboh [Nigeria]Source :
- International Journal of Alzheimer's Disease [ 2090-8024 ] ; 2014.
Abstract
This study sought to investigate the effect of infusions from green tea (
Url:
DOI: 10.1155/2014/586407
PubMed: 25243093
PubMed Central: 4138732
Affiliations:
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<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">Comparison of the Inhibition of Monoamine Oxidase and Butyrylcholinesterase Activities by Infusions from Green Tea and Some Citrus Peels</title><author><name sortKey="Ademosun, Ayokunle O" sort="Ademosun, Ayokunle O" uniqKey="Ademosun A" first="Ayokunle O." last="Ademosun">Ayokunle O. Ademosun</name><affiliation wicri:level="1"><nlm:aff id="I1">Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001</wicri:regionArea><wicri:noRegion>Akure 340001</wicri:noRegion></affiliation></author><author><name sortKey="Oboh, Ganiyu" sort="Oboh, Ganiyu" uniqKey="Oboh G" first="Ganiyu" last="Oboh">Ganiyu Oboh</name><affiliation wicri:level="1"><nlm:aff id="I1">Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001</wicri:regionArea><wicri:noRegion>Akure 340001</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PMC</idno><idno type="pmid">25243093</idno><idno type="pmc">4138732</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4138732</idno><idno type="RBID">PMC:4138732</idno><idno type="doi">10.1155/2014/586407</idno><date when="2014">2014</date><idno type="wicri:Area/Pmc/Corpus">000F68</idno><idno type="wicri:Area/Pmc/Curation">000F67</idno><idno type="wicri:Area/Pmc/Checkpoint">000872</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">000394</idno><idno type="wicri:Area/PubMed/Curation">000394</idno><idno type="wicri:Area/PubMed/Checkpoint">000394</idno><idno type="wicri:Area/Ncbi/Merge">001841</idno><idno type="wicri:Area/Ncbi/Curation">001841</idno><idno type="wicri:Area/Ncbi/Checkpoint">001841</idno><idno type="wicri:doubleKey">2090-8024:2014:Ademosun A:comparison:of:the</idno><idno type="wicri:Area/Main/Merge">000B54</idno><idno type="wicri:Area/Main/Curation">000B51</idno><idno type="wicri:Area/Main/Exploration">000B51</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a" type="main">Comparison of the Inhibition of Monoamine Oxidase and Butyrylcholinesterase Activities by Infusions from Green Tea and Some Citrus Peels</title><author><name sortKey="Ademosun, Ayokunle O" sort="Ademosun, Ayokunle O" uniqKey="Ademosun A" first="Ayokunle O." last="Ademosun">Ayokunle O. Ademosun</name><affiliation wicri:level="1"><nlm:aff id="I1">Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001</wicri:regionArea><wicri:noRegion>Akure 340001</wicri:noRegion></affiliation></author><author><name sortKey="Oboh, Ganiyu" sort="Oboh, Ganiyu" uniqKey="Oboh G" first="Ganiyu" last="Oboh">Ganiyu Oboh</name><affiliation wicri:level="1"><nlm:aff id="I1">Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001, Nigeria</nlm:aff><country xml:lang="fr">Nigeria</country><wicri:regionArea>Functional Foods and Nutraceuticals Unit, Department of Biochemistry, Federal University of Technology, PMB 704, Akure 340001</wicri:regionArea><wicri:noRegion>Akure 340001</wicri:noRegion></affiliation></author></analytic><series><title level="j">International Journal of Alzheimer's Disease</title><idno type="ISSN">2090-8024</idno><idno type="eISSN">2090-0252</idno><imprint><date when="2014">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en"><p>This study sought to investigate the effect of infusions from green tea (<italic>Camellia sinensis</italic>) and some citrus peels [shaddock (<italic>Citrus maxima</italic>), grapefruit (<italic>Citrus paradisi</italic>), and orange (<italic>Citrus sinensis</italic>)] on key enzymes relevant to the management of neurodegenerative conditions [monoamine oxidase (MAO) and butyrylcholinesterase (BChE)]. The total phenol contents and antioxidant activities as typified by their 2,2<sup>′</sup>-azino-bis(3-ethylbenzthiazoline-6-sulphonic acid) (ABTS) radicals scavenging abilities, ferric reducing antioxidant properties, and Fe<sup>2+</sup> chelating abilities were also investigated. Green tea had the highest total phenol (43.3 mg/g) and total flavonoid (16.4 mg/g) contents, when compared to orange [total phenol (19.6 mg/g), total flavonoid (6.5 mg/g)], shaddock [total phenol (16.3 mg/g), total flavonoid (5.2 mg/g)], and grapefruit [total phenol (17.7 mg/g), total flavonoid (5.9 mg/g)]. Orange (EC<sub>50</sub> = 1.78 mg/mL) had the highest MAO inhibitory ability, while green tea had the least MAO inhibitory ability (EC<sub>50</sub> = 2.56 mg/mL). Similarly, green tea had the least BChE inhibitory ability (EC<sub>50</sub> = 5.43 mg/mL) when compared to the citrus peels' infusions. However, green tea infusions had the strongest highest ABTS radical scavenging ability, reducing power, and Fe<sup>2+</sup> chelating ability. The inhibition of MAO and BChE activities by the green tea and citrus peels infusions could make them good dietary means for the prevention/management of neurodegenerative conditions.</p></div></front><back><div1 type="bibliography"><listBibl><biblStruct><analytic><author><name sortKey="Youdim, Mbh" uniqKey="Youdim M">MBH Youdim</name></author><author><name sortKey="Edmondson, D" uniqKey="Edmondson D">D Edmondson</name></author><author><name sortKey="Tipton, Kf" uniqKey="Tipton K">KF Tipton</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Riederer, P" uniqKey="Riederer P">P Riederer</name></author><author><name sortKey="Sofic, E" uniqKey="Sofic E">E Sofic</name></author><author><name sortKey="Rausch, Wd" uniqKey="Rausch W">WD Rausch</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Thomas, T" uniqKey="Thomas T">T Thomas</name></author></analytic></biblStruct><biblStruct><analytic><author><name sortKey="Mukherjee, Pk" 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Ademosun</name></noRegion><name sortKey="Oboh, Ganiyu" sort="Oboh, Ganiyu" uniqKey="Oboh G" first="Ganiyu" last="Oboh">Ganiyu Oboh</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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